Heritability of Intracortical Inhibition and Facilitation

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Heritability of intracortical inhibition and facilitation.

The present twin study investigates heritability of motor cortex excitability, measured by the paired pulse transcranial magnetic stimulation technique. Specifically, intracortical facilitation (ICF) and inhibition (ICI) and corticospinal excitability were tested in monozygotic (MZ), dizygotic (DZ), and unrelated pairs (UP). Robust ICF and ICI effects were found, with a higher similarity of MZ ...

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Influence of short-interval intracortical inhibition on short-interval intracortical facilitation in human primary motor cortex.

Using the paired-pulse paradigm, transcranial magnetic stimulation (TMS) has revealed much about the human primary motor cortex (M1). A preceding subthreshold conditioning stimulus (CS) inhibits the excitability of the motor cortex, which is named short-interval intracortical inhibition (SICI). In contrast, facilitation is observed when the first pulse (S1) is followed by a second one at thresh...

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Intracortical inhibition and facilitation in different representations of the human motor cortex.

Intracortical inhibition and facilitation in different representations of the human motor cortex. J. Neurophysiol. 80: 2870-2881, 1998. Intracortical inhibition (ICI) and intracortical facilitation (ICF) of the human motor cortex can be studied with paired transcranial magnetic stimulation (TMS). Plastic changes and some neurological disorders in humans are associated with changes in ICI and IC...

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Reduced intracortical inhibition and facilitation in the primary motor tongue representation of adults who stutter.

OBJECTIVE We aimed at detecting neurophysiological changes, in the primary motor tongue representation in adults with persistent stuttering. METHODS Using transcranial magnetic stimulation in 12 patients and 14 controls, we examined motor threshold, motor-evoked potential (MEP) input-output curve, short-term intracortical inhibition (SICI) and intracortical facilitation (ICF), based on eight ...

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ژورنال

عنوان ژورنال: Journal of Neuroscience

سال: 2009

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.2112-09.2009